Research on stem cells, including embryonic and adult stem cells
Latest Research Highlights
From November 2025
Neural stem cell transplantation significantly restores forelimb function in primates with spinal cord injuries, showcasing the potential of stem cells in regenerative medicine, ref: Sinopoulou doi.org/10.1038/s41587-025-02865-9/
Patient-derived iPSCs enable large-scale drug screening for ALS, identifying potential combinatorial therapies, ref: Bye doi.org/10.1038/s41593-025-02118-7/
Heme biosynthesis is a selective dependency in AML, promoting self-renewal of leukemic stem cells, ref: Lewis doi.org/10.1016/j.cell.2025.10.028/
RNA innate immunity poses challenges for interspecies chimerism with human pluripotent stem cells, highlighting the importance of the stem cell microenvironment, ref: Hu doi.org/10.1016/j.cell.2025.10.039/
The transition to a Paneth-like cell state in colorectal cancer cells allows evasion of dual KRAS and EGFR therapy, indicating plasticity in cancer cell responses, ref: Zhang doi.org/10.1016/j.ccell.2025.10.010/
Innovative techniques like GREGoR enhance genomics for rare diseases, improving genetic diagnostics, ref: Dawood doi.org/10.1038/s41586-025-09613-8/
Mesenchymal progenitor cells engineered to resist senescence offer insights into rejuvenation strategies for aging-related decline in tissue regeneration, ref: Gorbunova doi.org/10.1016/j.cell.2025.10.011/