Infant-type hemispheric glioma is predominantly non-metastatic and diagnosed at a median age of 3.4 months, ref: Chavaz doi.org/10.1093/neuonc/
Single-cell multi-omics reveals metabolism-linked epigenetic reprogramming as a driver of therapy-resistant medulloblastoma, ref: Veo doi.org/10.1038/s41467-025-65466-9/
Germline pathogenic variants are present in 23.3% of pediatric CNS tumor patients, impacting treatment outcomes, ref: Corbett doi.org/10.1038/s41467-025-65190-4/
Focused ultrasound can effectively open the blood-brain barrier in pediatric diffuse midline glioma patients, enhancing drug delivery, ref: Wu doi.org/10.1126/scitranslmed.adq6645/
Executive dysfunction in children with focal cortical dysplasia is associated with structural brain anomalies, ref: Cohen doi.org/10.1212/WNL.0000000000214352/
Portable MRI shows promise in monitoring brain injury in pediatric ECMO patients, potentially improving clinical outcomes, ref: Wallisch doi.org/10.1161/JAHA.125.043434/
Immune cell densities in pediatric medulloblastoma correlate with prognosis, highlighting the role of the immune microenvironment, ref: Chen doi.org/10.1016/j.ebiom.2025.106043/
Systemic mRNA vaccines elicit immune activation in canine glioma, suggesting potential for pediatric glioma immunotherapy, ref: Carrera-Justiz doi.org/10.1136/jitc-2025-011817/