Impaired cAMP-PKA-CREB1 signaling drives mitochondrial dysfunction in skeletal muscle during cancer cachexia, highlighting PDE4D as a therapeutic target (ref: Angelino doi.org/10.1038/s42255-025-01397-5/).
The IRE1α/XBP1 pathway is a key contributor to muscle wasting during pancreatic cancer cachexia, suggesting potential therapeutic strategies (ref: Joshi doi.org/10.1038/s44321-025-00337-w/).
Anti-MDA5 positive patients exhibit shorter disease duration and higher rates of ILD, while anti-ARS positive patients have better prognosis (ref: Li doi.org/10.3389/fimmu.2025.1674437/).
The LOCCM index demonstrates strong predictive power for progressive pulmonary fibrosis in patients with anti-synthetase syndrome (ref: Zhu doi.org/10.1186/s12931-025-03414-3/).
High-intensity interval training significantly improves aerobic capacity and muscle endurance in patients with recent-onset idiopathic inflammatory myopathies (ref: Andreasson doi.org/10.1016/j.ebiom.2025.106051/).
Swimming exercise reverses diabetic myopathy and promotes mitochondrial adaptations in a rat model (ref: Catinelli doi.org/10.1016/j.bbadis.2025.168126/).
N-acetylcysteine prevents cisplatin-induced muscle atrophy by inducing myogenic microRNAs and maintaining redox balance (ref: Aremu doi.org/10.3390/antiox14111344/).
Acute fish oil supplementation may mitigate exercise-induced muscle damage and enhance recovery (ref: Lee doi.org/10.3390/nu17213408/).