Switching from APOE4 to APOE2 in mice significantly reduces Alzheimer's disease risk and improves cognition (ref: Golden doi.org/10.1038/s41593-025-02094-y/)
Single-nucleus transcriptomics reveals motor neuron glutamate overactivation in ALS, highlighting cellular vulnerabilities (ref: Takeuchi doi.org/10.1093/brain/)
Infant-type hemispheric gliomas are predominantly non-metastatic and diagnosed early, necessitating tailored treatment (ref: Chavaz doi.org/10.1093/neuonc/)
BTK inhibition in multiple sclerosis limits inflammation and promotes regulatory B cells, indicating a novel therapeutic strategy (ref: Dybowski doi.org/10.1212/NXI.0000000000200510/)
Vitamin C deprivation in guinea pigs leads to significant neurodevelopmental changes, linking nutrition to brain health (ref: Čapo doi.org/10.3390/nu17213484/)
A noninvasive RT-QuIC assay for prion disease diagnosis shows high specificity, offering a promising diagnostic tool (ref: Dong doi.org/10.1038/s41598-025-25310-y/)
Molecular characterization of oxaliplatin-induced peripheral neurotoxicity reveals a complex spectrum of painful manifestations (ref: Pozzi doi.org/10.1111/jns.70078/)