The management of meningiomas involves various surgical techniques and considerations for patient outcomes. A study on hyperostosing sphenoid wing meningiomas highlighted that postoperative vision was stable or improved in 98% of patients, although complications occurred in 44%, necessitating additional surgeries for some (ref: Dalle Ore doi.org/10.3171/2019.12.JNS192543/). Another investigation into preoperative embolization for WHO grade I meningiomas found that while it did not significantly enhance surgical outcomes, it did correlate with a greater chance of clinical improvement (ref: Przybylowski doi.org/10.3171/2020.1.JNS19788/). Furthermore, the identification of microRNA markers for predicting tumor recurrence offers a promising avenue for tailoring postoperative management, with significant prognosticators identified (ref: Slavik doi.org/10.1093/neuros/). Additionally, a retrospective analysis of primary dural lymphomas revealed that they accounted for 6.3% of primary CNS lymphomas, emphasizing the need for further clinical experience in this rare condition (ref: Karschnia doi.org/10.1002/cncr.32834/). Racial and socioeconomic factors also play a crucial role, as disparities in treatment and survival outcomes were noted, with lower socioeconomic status correlating with reduced odds of receiving gross total resection and radiotherapy (ref: Bhambhvani doi.org/10.1007/s11060-020-03455-2/).

Research into socioeconomic and racial disparities in meningioma treatment reveals significant inequalities in patient outcomes. A population-based study indicated that patients from lower socioeconomic backgrounds had significantly reduced odds of receiving gross total resection (GTR) and radiotherapy, leading to worse survival rates compared to their higher socioeconomic counterparts (ref: Bhambhvani doi.org/10.1007/s11060-020-03455-2/). Additionally, a systematic review highlighted that race plays a critical role in survival outcomes, with White non-Hispanic patients generally experiencing better survival rates compared to Black non-Hispanic patients, particularly in cases where GTR was achieved (ref: Elder doi.org/10.1016/j.wneu.2020.02.120/). The socioeconomic burden of meningioma surgery also impacts quality of life, with long-term impairments noted even after curative interventions, suggesting that socioeconomic factors may influence both treatment access and postoperative recovery (ref: Wirsching doi.org/10.1007/s11136-020-02461-1/). These findings underscore the need for targeted interventions to address these disparities and improve outcomes for underrepresented populations.

Molecular and genetic research into meningiomas has identified critical markers that may enhance prognostic accuracy and treatment strategies. A study focusing on microRNA profiling found that specific markers, including miR-15a-5p, miR-146a-5p, and miR-331-3p, were significant predictors of tumor recurrence, suggesting that these biomarkers could guide postoperative management and therapeutic decisions (ref: Slavik doi.org/10.1093/neuros/). Additionally, the MOBI-Kids study provided insights into the clinical presentation of brain tumors in young populations, revealing that delays in diagnosis can be significant, with 12% of cases exceeding one year (ref: Zumel-Marne doi.org/10.1007/s11060-020-03437-4/). This highlights the importance of early detection and the potential role of genetic factors in influencing tumor behavior and patient outcomes. Overall, the integration of molecular insights into clinical practice may lead to more personalized treatment approaches for meningioma patients.

Innovations in surgical techniques for meningioma resection have significantly improved patient outcomes. A retrospective review of surgical outcomes for hyperostosing sphenoid wing meningiomas demonstrated that 98% of patients experienced stable or improved vision post-surgery, although complications were noted in 44% of cases (ref: Dalle Ore doi.org/10.3171/2019.12.JNS192543/). The use of expanded endoscopic approaches has been highlighted as advantageous, allowing for reduced morbidity associated with traditional craniotomies while providing effective access to the vascular supply of tumors (ref: Silveira-Bertazzo doi.org/10.1007/s00701-020-04277-x/). Additionally, the debate surrounding the contralateral approach for tuberculum sellae meningiomas continues, with discussions on its safety and effectiveness compared to ipsilateral approaches (ref: Voznyak doi.org/10.1007/s10143-020-01278-3/). These advancements in surgical techniques not only enhance the safety and efficacy of meningioma resections but also contribute to improved visual outcomes and overall patient satisfaction.

Radiotherapy and adjuvant treatments for meningiomas have evolved, with recent studies exploring their efficacy and safety. A retrospective series on CyberKnife radiotherapy for olfactory groove meningiomas indicated that this treatment modality is both safe and effective, with a significant number of patients achieving disease control (ref: Liu doi.org/10.1186/s13014-020-01506-6/). Furthermore, the combination of peptide receptor radionuclide therapy (PRRT) with external beam radiotherapy (EBRT) showed promising results, with a median progression-free survival of 107.7 months in patients receiving this multimodal approach (ref: Hartrampf doi.org/10.1016/j.ctro.2020.03.002/). These findings suggest that integrating radiotherapy with surgical interventions can lead to better management of advanced symptomatic meningiomas. However, the need for careful patient selection and monitoring remains critical to optimize treatment outcomes and minimize potential complications.

The epidemiology of meningiomas and associated risk factors have been the focus of recent studies, revealing significant insights into their incidence and potential environmental influences. A study examining the association between outdoor air pollution and brain tumors found that exposure to benzene was linked to an increased risk of malignant and benign brain tumors, particularly in men (ref: Wu doi.org/10.1093/jncics/). Additionally, research on transient perifocal edema following radiosurgery for intraventricular meningiomas indicated a high incidence of this complication, suggesting that careful monitoring is necessary post-treatment (ref: Mindermann doi.org/10.1007/s00701-020-04281-1/). Furthermore, factors such as patient age and tumor location were correlated with pre- and postoperative seizure occurrences, highlighting the complexity of managing meningiomas (ref: Puri doi.org/10.1016/j.clineuro.2020.105779/). These findings emphasize the importance of understanding both environmental and clinical risk factors in the management of meningiomas.

Quality of life (QoL) following meningioma surgery is a critical area of research, with studies indicating that many patients experience long-term impairments despite curative interventions. A cross-sectional survey revealed that socioeconomic factors significantly impact post-operative QoL, with certain patients at higher risk for inferior outcomes (ref: Wirsching doi.org/10.1007/s11136-020-02461-1/). Additionally, guidelines for managing pediatric meningiomas emphasize the unique challenges faced by younger patients, as these tumors are rare in this population and often require treatment strategies adapted from adult data (ref: Szychot doi.org/10.1080/02688697.2020.1726286/). The interplay between surgical outcomes, socioeconomic status, and quality of life underscores the need for comprehensive care approaches that address both medical and psychosocial aspects of recovery for meningioma patients.

Pediatric meningiomas present unique challenges in management due to their rarity and the distinct characteristics of tumors in younger patients. The Children's Cancer and Leukaemia Group has established guidelines emphasizing the need for tailored approaches in treating meningiomas in children, teenagers, and young adults, as these tumors account for only a small percentage of pediatric central nervous system tumors (ref: Szychot doi.org/10.1080/02688697.2020.1726286/). The absence of collaborative prospective trials complicates the development of consensus treatment protocols, often necessitating reliance on adult data for guidance. This highlights the importance of ongoing research and collaboration to improve outcomes for pediatric patients with meningiomas, ensuring that their unique clinical needs are adequately addressed.