Research on CNS nanopore sequencing

From September 2025

Long-read sequencing reveals RNA isoform diversity in neuropsychiatric disorders, enhancing understanding of gene expression (ref: De Paoli-Iseppi doi.org/10.1186/s13059-025-03724-1/)
Single-nuclei long-read RNA sequencing uncovers cell-type-specific splicing dysregulation in frontotemporal dementia (ref: Belchikov doi.org/10.1016/j.celrep.2025.116198/)
SKiM classifier improves metagenomic read classification for Oxford Nanopore sequencing (ref: Schneggenburger doi.org/10.1093/bioinformatics/)
Methylation profiling aids in accurate CNS tumor diagnosis post-radiation therapy (ref: Handoko doi.org/10.3892/br.2025.2043/)
tDCS shows potential for long-term changes in brain function, comparable to TMS (ref: Agrawal doi.org/10.3390/ijms26178634/)
Polyadenylation dynamics during LTP reveal critical insights into synaptic plasticity mechanisms (ref: Gumińska doi.org/10.1261/rna.080485.125/)
Cacna1e splice variants cataloged, highlighting alternative splicing's impact on calcium channel function (ref: Bhuiyan doi.org/10.1186/s12864-025-11887-1/)
Nanopore sequencing techniques advance understanding of transcriptomic responses in various biological contexts.

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